Leaders Berekum Chelsea thrashed New Edubiase United 3-0 at home to go 14 points above their chasers and All Stars derailed Hearts of Oak 1-0 in Wa.
After a barren first half, Emmanuel Clottey opened the scoring just after the hour mark by prodding home a Mohammed Abdul Basit cross.
Captain Basit added the second in the 73rd minute with another header and Clottey sealed it with a finish in the 86th minute.
Wa All Stars avoided a relegation battle by recording a vital solitary 1-0 win over Hearts of Oak thanks to Godfred Kwame Gyasi's 71st minute goal.
AshantiGold needed two first half goals to post a 2-0 win over Heart of Lions at the Len Clay Sports Stadium.
Aminu Mohammed's 17th minute goal was cushion by Yakubu Mohammed who converted a 73rd minute penalty.
Liberty Professionals gave their relegation battle a boost with a 2-0 win over Real Tamale United, second-bottom, on goals from Kevin Koukou and Michael Appiah in the second-half.
Kwame Frimpong scored a spectacular to give Ebusua Dwarfs a 1-0 win over defending champions Aduana Stars at the Robert Mensah Park.
Mighty Jets beat Berekum Arsenals 2-1 at the VRA Park in Akosombo but remained in the drop.
Bottom-club BA Stars frustrated second-place Medeama Sporting Club to a goalless draw at the Sunyani Coronation Park.
Asante Kotoko play King Faisal in the late kick-off