Ghanaian pair Joseph Alfred Duncan and Claud Agyapong will work under new coach Cristian Bucchi at Sassuolo.
The Serie A outfit confirmed the appointment of the former Perugia boss.
Eusebio Di Francesco left the Neroverdi earlier this month to join Roma, meaning there was a vacancy on the bench at Mapei Stadium.
Duncan has been a subject of intense interest from several clubs in Italy including AC Milan, Roma and Inter.