Asante Kotoko marked their revival with a 0-2 win at Wa All Stars and Real Tamale United broke a 33-year jinx of beating Hearts of Oak in Accra.
Striker Nathaniel Asamoah who joined Kotoko for the second round punished his former side by getting both goals.
Kotoko have now moved 8th on the standings and are 14 points adrift the top.
Relegation battlers RTU needed a Sumaila Nyaya goal to shock Hearts of Oak 0-1 in Accra, the first since making their league debut in 1978.
Leaders Chelsea needed an injury-time winner to claim a 2-1 victory over Mighty Jets at the Golden City Park to maintain a seven-point gap at the top.
Samuel Ato Ghansah on the stroke of regulation time canceled out Bismark Idan's opener for Chelsea which came through a spot kick.
But the home side run away winners with Obed Owusu grabbing the winner in added on time.
New Edubiase still stay second after defeating Heart of Lions 2-1 at the Gyemfis Park.
Aduana Stars won 2-1 against Berekum Arsenals to claim the bragging rights of the derby clash at the Dormaa Park.
Alex Anim and Daniel Dankwa scored for Aduana as Nana Poku pulled one back for the Gunners.
Isaac Donkor handed Liberty Professionals a share of the spoils at the Robert Mensah Stadium where they drew 1-1 with Ebusua Dwarfs after captain Bismark Asiedu had put the home team in the lead.
Bottom side B.A. Stars beat AshantiGold 1-0 at the Sekondi Sports Stadium, their adopted grounds as they serve the first of two consecutive home match ban.
Substitute Joe Debrah scored the winner for the bottom side.
King Faisal drew 2-2 with Medeama at the Baba Yara in a match of equals.
Source:Ghanafa.org