Four clubs are caught up in the mix with the Glo Premier League set to draw the curtains on Sunday.
Berekum Arsenals, AshantiGold, Mighty Jets and King Faisal are still mired in the relegation struggles with just one place in the second tier of Ghana football yet to be confirmed.
The 2010-11 season will go down as one of the most dramatic since the dawn of the Premier League with Berekum Chelsea dominating the headlines by winning the competition while Real Tamale United ended their 33-year stay in the topflight.
But the final day matches would end the nervous wait of confirming which other side joins RTU and B.A. Stars into relegation.
The fixtures involving the 'group of four' would generate all the interest.
Arsenals, serving a three-match home ban would play away from home when they welcome New Edubiase to the Robert Mensah Stadium in Cape Coast in a must-win game.
Champions, Berekum Chelsea visits AshantiGold, who also need to win at the Len Clay Stadium.
King Faisal, who are third from bottom are at home to Accra Hearts of Oak at the Baba Yara Stadium.
Mighty Jets, who are hoping to avoid return to the Division One stables after just one season in the elite division would take on Ebusua Dwarfs at the Akosombo Park.
The other matches would see Medeama, who are attempting to finish second host Asante Kotoko in Tarkwa with Liberty Professionals taking on Wa All Stars at home.
Both RTU and B.A. Stars would be bidding goodbyes to the premiership campaign in the final games.
RTU would play Aduana Stars at home with B.A. Stars visiting Heart of Lions        in Kpando to end a long season.
Source: Ghanafa.org