Ghana midfielder Kevin Prince Boateng was sent off as his Italian side AC Milan were beaten 2-0 by Juventus on Sunday.
Boateng was making a quicker-than-expected return from injury after three weeks on the sidelines because of a rib problem.
But a moment of indecision by the Ghanaian helped Juventus to remain unbeaten and move to the top of Italy's Serie A.
Following more than 85 minutes of scoreless action, Marchisio broke the match open with just three minutes left in normal time when he scored to the bottom right from the middle of the area.
Milan's misery was compounded in the 89th minute when Kevin-Prince Boateng was dismissed following a second yellow card for hitting Giorgio Chiellini with a flailing arm.
Boateng then received his marching orders after he was shown a second yellow for throwing out an arm which caught Chiellini in the face.
Then, in the third minute of stoppage time, Marchisio completed his double with a long-range volley which somehow slipped through Abbiati’s grasp and into the net.